If you’re sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while you’re using Cymbalta. Before approving coverage for Cymbalta, your insurance company may require you to get prior authorization. hope house boston review and compare with eco sober house This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. The insurance company will review the prior authorization request and decide whether the drug will be covered.
Is Cymbalta a kind of drug called an SSRI?
For this use, the recommended starting dose is 40 mg to 60 mg. It’s vital to always take the dosage your medical professional prescribes. Cymbalta has a boxed warning about suicidal thoughts and behaviors.
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SNRIs and SSRIs are both used to treat mental health conditions such as depression and anxiety. If you’d like to know more about using Cymbalta instead of duloxetine oral capsules, talk with your doctor. View this Healthline article to learn more about the differences between generic and brand-name drugs. Duloxetine oral capsules are a generic drug, which means they’re an exact copy of the active drug in a brand-name medication.
Generic Name(S): duloxetine
These generics contain the same active ingredient, duloxetine, and are designed to be therapeutically equivalent to Cymbalta.Generic versions of duloxetine are typically more affordable compared to the brand-name Cymbalta. They undergo strict regulatory standards to ensure their safety, quality, and efficacy. It is important to consider both the availability and cost of Cymbalta when discussing treatment options with your healthcare provider.
Symptoms of overdose
It is important to note that Cymbalta should only be taken under the supervision and prescription of a healthcare professional. It is also important to discuss any other medications or health conditions with the doctor to ensure there are no potential interactions or contraindications. Approximately 15.7% (79/503) of the CYMBALTA-treated patients in 13-week, placebo-controlled adult trials for chronic pain due to OA discontinued treatment due to an adverse reaction, compared with 7.3% (37/508) for placebo-treated patients.
For adults ages 65 years and older, the recommended starting dosage for GAD is 30 mg once per day. Doctors may then increase the dosage to 60 mg once per day if they determine it’s safe to do so. Antidepressants like duloxetine can increase your risk of suicidal thoughts and behavior, especially in children and adolescents mdma withdrawal timeline symptoms + detox treatment options between the ages of who have major depressive disorder. Most doctors will begin patients at a low dose and increase it slowly over a number of weeks until a dose that works for you is reached. Dosages range from 20 mg to 120 mg, with most people taking about 60 mg per day for anxiety and depression.
The maximum dosage of Cymbalta to treat GAD in adults of any age is 120 mg once per day. A delayed-release drug doesn’t break down in your body right away. This helps certain drugs, such as Cymbalta, work for a longer time and more effectively.
Keep in mind that conditions such as major depressive disorder, which this drug is used to treat, can also cause sexual side effects. So it may be hard for you to tell if these side effects are caused by duloxetine or the condition you’re taking the drug to treat. Older adults may be more sensitive to the side effects of this drug, especially bleeding, dizziness, lightheadedness, or loss of coordination. Older adults are also more likely to develop a type of mineral imbalance (hyponatremia), especially if they are also taking “water pills” (diuretics) with this medication. Dizziness, lightheadedness, or loss of coordination can increase the risk of falling. CYMBALTA is indicated for the treatment of chronic musculoskeletal pain in adults.
Women who discontinue antidepressants during pregnancy are more likely to experience a relapse of major depression than women who continue antidepressants. This finding is from a prospective, longitudinal study that followed 201 pregnant women with a history of major depressive disorder who were euthymic and taking antidepressants at the beginning of pregnancy. Consider the risk of untreated depression when discontinuing or changing treatment with antidepressant medication during pregnancy and postpartum. In an analysis of patients from all placebo-controlled trials, patients treated with CYMBALTA reported a higher rate of falls compared to patients treated with placebo. Risk appears to be related to the presence of orthostatic decrease in BP. Consideration should be given to dose reduction or discontinuation of CYMBALTA in patients who experience symptomatic orthostatic hypotension, falls and/or syncope during CYMBALTA therapy.
These medications are commonly prescribed to treat the same conditions, including depression, anxiety, and fibromyalgia. Also, some of the medications may be prescribed off-label for treating these conditions. “Off label” use is when a medication is prescribed for a condition that it isn’t approved to treat.
- Duloxetine oral capsule can interact with other medications, vitamins, or herbs you may be taking.
- Antidepressants are a popular treatment choice for depression.
- These lists contain examples of serious side effects that can occur with Cymbalta, with Effexor XR, or with both drugs (when taken individually).
- Researchers in clinical trials didn’t measure how quickly Cymbalta started working for any of the conditions the drug is approved to treat.
There is no specific antidote to a CYMBALTA overdosage, but if serotonin syndrome ensues, specific treatment (such as with cyproheptadine and/or temperature control) may be considered. The pharmacokinetics of duloxetine after a single dose of 40 mg were compared in healthy elderly females (65 how long does crack cocaine stay in your system to 77 years) and healthy middle-age females (32 to 50 years). There was no difference in the Cmax, but the AUC of duloxetine was somewhat (about 25%) higher and the half-life about 4 hours longer in the elderly females. Dosage adjustment based on the age of the adult patient is not necessary.
If you notice other effects not listed above, contact your doctor or pharmacist. Check your blood pressure regularly and tell your doctor if the results are high. Duloxetine is also used to treat fibromyalgia (muscle pain and stiffness) and chronic (long-lasting) pain that is related to muscles and bones. Withdrawal symptoms listed in 48 case reports (in the first quarter of 2012) included anger, crying, dizziness and suicidal ideation.
Or they may have you take a different drug to treat your condition. If you’re interested in finding an alternative to Cymbalta, talk with your doctor. They can tell you about other medications that may work well for you. Effexor XR is available as a generic drug called venlafaxine ER. This was one of the more common side effects of the drug in clinical trials. Because of the risk of withdrawal symptoms, you should not abruptly stop taking Cymbalta.
The recommended Cymbalta dosage for treating fibromyalgia or long-term pain in the muscles, bones, or joints in adults is 60 mg once per day. But if you have one of these conditions, your doctor will likely start you on 30 mg once per day. If you’re doing well on this dose, your doctor may increase your dose to 60 mg once per day. Duloxetine oral capsules have a boxed warning about an increased risk of suicidal thoughts and behaviors. This risk affects children, adolescents, and young adults who take medications such as duloxetine to treat depression. Duloxetine belongs to a group of drugs called selective norepinephrine reuptake inhibitors (SNRIs).
The recommended starting dose for treating fibromyalgia with Cymbalta is usually 30 mg once daily, and it may be increased to 60 mg once daily based on individual response and tolerability. The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder (OCD), or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over 4400 patients. The pooled analyses of placebo-controlled trials in adults with MDD or other psychiatric disorders included a total of 295 short-term trials (median duration of 2 months) of 11 antidepressant drugs in over 77,000 patients.
Data from published literature report the presence of duloxetine in human milk (see Data). There are reports of sedation, poor feeding, and poor weight gain in infants exposed to duloxetine through breast milk (see Clinical Considerations). There are no data on the effect of duloxetine on milk production. Duloxetine administered orally to either male or female rats prior to and throughout mating at doses up to 45 mg/kg/day (3 times the MRHD given to adolescents on a mg/m2 basis) did not alter mating or fertility. Advise breastfeeding women using CYMBALTA to monitor infants for sedation, poor feeding and poor weight gain and to seek medical care if they notice these signs [see Use In Specific Populations].
The patients had a baseline pain score of 6.5 on an 11-point scale ranging from 0 (no pain) to 10 (worse possible pain). Starting CYMBALTA in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome [see DOSAGE AND ADMINISTRATION and WARNINGS AND PRECAUTIONS]. The stated frequencies of adverse reactions represent the proportion of patients who experienced, at least once, one treatment-emergent adverse reaction of the type listed. A reaction was considered treatment-emergent if it occurred for the first time or worsened while receiving therapy following baseline evaluation. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.